Anna Orlova Selected Research

Gamma Cameras (Gamma Camera)

11/2014	188Re-ZHER2:V2, a promising affibody-based targeting agent against HER2-expressing tumors: preclinical assessment.
7/2011	Influence of an aliphatic linker between DOTA and synthetic Z(HER2:342) Affibody molecule on targeting properties of the (111)In-labeled conjugate.
7/2010	Targeting of HER2-expressing tumors using 111In-ABY-025, a second-generation affibody molecule with a fundamentally reengineered scaffold.
11/2007	(99m)Tc-maEEE-Z(HER2:342), an Affibody molecule-based tracer for the detection of HER2 expression in malignant tumors.
3/2007	In vivo evaluation of cysteine-based chelators for attachment of 99mTc to tumor-targeting Affibody molecules.
3/2007	Synthetic affibody molecules: a novel class of affinity ligands for molecular imaging of HER2-expressing malignant tumors.
4/2006	Tumor imaging using a picomolar affinity HER2 binding affibody molecule.

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Anna Orlova Research Topics

Disease

180	Neoplasms (Cancer) 05/2024 - 08/2003
36	Prostatic Neoplasms (Prostate Cancer) 05/2024 - 04/2011
20	Breast Neoplasms (Breast Cancer) 03/2023 - 08/2004
14	Neoplasm Metastasis (Metastasis) 05/2023 - 11/2004
13	Carcinoma (Carcinomatosis) 05/2020 - 11/2004
5	Ovarian Neoplasms (Ovarian Cancer) 08/2022 - 06/2006
5	Glioblastoma (Glioblastoma Multiforme) 01/2018 - 08/2003
4	Glioma (Gliomas) 01/2018 - 08/2003
3	Renal Cell Carcinoma (Grawitz Tumor) 01/2023 - 11/2016
3	Inflammation (Inflammations) 12/2019 - 01/2014
3	Colorectal Neoplasms (Colorectal Cancer) 01/2014 - 10/2005
2	Pancreatic Neoplasms (Pancreatic Cancer) 02/2023 - 06/2020
2	Lymphoma (Lymphomas) 01/2023 - 05/2020
2	Disease Progression 01/2021 - 06/2019
2	Squamous Cell Carcinoma of Head and Neck 04/2016 - 11/2004
2	Neoplasm Micrometastasis 09/2009 - 10/2005
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 04/2024
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 04/2024
1	Type 2 Diabetes Mellitus (MODY) 12/2023
1	Experimental Neoplasms 06/2023
1	Wounds and Injuries (Trauma) 01/2023
1	Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous) 12/2022

Drug/Important Bio-Agent (IBA)

62	Radioisotopes (Radionuclides)IBA 05/2024 - 04/2004
30	ErbB Receptors (EGF Receptor)IBA 01/2023 - 08/2004
27	Proteins (Proteins, Gene)FDA Link 04/2023 - 04/2006
24	1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidIBA 10/2020 - 02/2007
22	Bombesin Receptors (Bombesin Receptor)IBA 04/2024 - 01/2013
18	Chelating AgentsIBA 04/2024 - 02/2007
17	Trastuzumab (Herceptin)FDA Link 04/2023 - 08/2005
14	AntigensIBA 05/2024 - 10/2005
14	Monoclonal AntibodiesIBA 08/2022 - 11/2004
13	1,4,7- triazacyclononane- N,N',N''- triacetic acid (NOTA)IBA 04/2024 - 05/2011
12	1- (1,3- carboxypropyl)- 4,7- carboxymethyl- 1,4,7- triazacyclononaneIBA 04/2024 - 03/2012
11	human ERBB2 proteinIBA 08/2022 - 06/2010
9	Designed Ankyrin Repeat ProteinsIBA 04/2024 - 01/2018
9	Epidermal Growth Factor (EGF)IBA 01/2021 - 08/2003
8	BombesinIBA 03/2023 - 01/2013
8	Cys-ZHER2-342 affibodyIBA 01/2018 - 02/2007
7	Peptides (Polypeptides)IBA 04/2024 - 01/2013
7	Epithelial Cell Adhesion MoleculeIBA 02/2023 - 02/2020
6	LigandsIBA 03/2024 - 04/2006
6	AlbuminsIBA 02/2022 - 01/2018
6	Tyrosine Kinase InhibitorsIBA 01/2021 - 11/2014
6	AntibodiesIBA 06/2020 - 08/2003
6	Pentetic Acid (DTPA)FDA LinkGeneric 10/2019 - 08/2003
6	AndrogensIBA 07/2014 - 04/2011
5	Immunoconjugates (Immunoconjugate)IBA 01/2023 - 01/2018
5	Indium-111IBA 07/2021 - 04/2007
4	Phosphotransferases (Kinase)IBA 04/2024 - 10/2010
4	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 04/2024 - 03/2009
4	Hormones (Hormone)IBA 03/2023 - 04/2011
4	seribantumabIBA 02/2023 - 01/2018
3	Photosensitizing Agents (Photosensitizers)IBA 12/2021 - 07/2010
3	Peptide Nucleic AcidsIBA 01/2018 - 01/2016
3	Biomarkers (Surrogate Marker)IBA 01/2018 - 07/2010
3	ABY-025IBA 01/2016 - 05/2011
3	Cysteine (L-Cysteine)FDA Link 04/2015 - 03/2007
2	Amino Acids FDA Link 04/2024 - 06/2012
2	Oxygen (Dioxygen)IBA 01/2022 - 02/2017
2	1-phenyl-3,3-dimethyltriazene (PDT)IBA 12/2021 - 02/2021
2	Aligeron (AS 2)IBA 01/2021 - 06/2010
2	EnzymesIBA 01/2020 - 11/2016
2	Transcription Factors (Transcription Factor)IBA 12/2019 - 02/2019
2	CobaltIBA 11/2019 - 01/2017
2	Carbonic Anhydrase IXIBA 10/2019 - 11/2016
2	Cetuximab (Erbitux)FDA Link 01/2019 - 04/2011
2	Technetium (Technetium 99m)IBA 01/2018 - 03/2006
2	Immunoglobulins (Immunoglobulin)IBA 01/2018 - 01/2016
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 04/2016 - 04/2011
2	Oncogene Proteins (Oncogene Protein)IBA 10/2015 - 06/2006
2	IndiumIBA 06/2014 - 11/2007
2	IodineIBA 06/2014 - 03/2006
2	IsotopesIBA 07/2013 - 11/2004
2	RadiopharmaceuticalsIBA 03/2011 - 03/2007
2	benzyl-DTPAIBA 09/2007 - 08/2003
2	Benzoates (Benzoate)IBA 07/2006 - 11/2004
1	Immune Checkpoint ProteinsIBA 04/2024
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 04/2024
1	Neprilysin (Neutral Endopeptidase)IBA 04/2024
1	glutamyl-glutamic acid (Glu-Glu)IBA 04/2024
1	glycyl-glycyl-glycine (triglycine)IBA 04/2024
1	PSMA-11IBA 12/2023
1	Mechanistic Target of Rapamycin Complex 1IBA 12/2023
1	Glucose (Dextrose)FDA LinkGeneric 12/2023
1	Metformin (Glucophage)FDA LinkGeneric 12/2023
1	polyvinylidene fluoride (PVDF)IBA 06/2023
1	PolymersIBA 06/2023
1	Bacterial ToxinsIBA 02/2023
1	ProdrugsIBA 01/2023
1	Peptide Hydrolases (Proteases)FDA Link 01/2023
1	FRAX597IBA 12/2022

Therapy/Procedure

85	Therapeutics 04/2024 - 08/2004
7	Gamma Cameras (Gamma Camera) 11/2014 - 04/2006
5	Precision Medicine 04/2024 - 10/2015
3	Radiotherapy 05/2024 - 12/2019
2	Castration 05/2024 - 01/2023
2	Investigational Therapies (Experimental Therapy) 01/2023 - 12/2020
2	Immunotherapy 01/2018 - 01/2014
2	Radioimmunotherapy 06/2013 - 10/2005
1	Lasers (Laser) 01/2023